منابع مشابه
Membrane traffic: Cycling lipids
One of the more fascinating problems in biology is to understand the nerve signalling that enables us to think and feel. The transmission of nerve impulses across synapses is accomplished by the release of signalling molecules, known as neurotransmitters, at nerve terminals. Neurotransmitters are stored in synaptic vesicles and, after the nerve has received the appropriate stimulus, they are re...
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It is a very great honour to have been awarded the Biochemical Society’s Morton Lectureship for 1994. T o be chosen by one’s peers for an award of this stature is indeed the ultimate reward for one’s life’s work, even more so when one considers the high level of achievement reached by Professor R.A. Morton himself and by the previous awardees. This award is particularly gratifying to me in reca...
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All biological membranes contain lipids that prefer to adopt a non-bilayer phase. Recent results suggest that, in the thylakoid membrane, membrane proteins force all the lipids to adopt a bilayer structure, and that the non-bilayer-forming lipids in the thylakoid membrane serve to drive the formation of membrane stacks.
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Introduction Numerous studies have demonstrated the presence of potassium selective channels in membranes internal organelles. These channels are essential to a large variety of cellular processes including intracellular 2+ a signaling, protein recycling, charge neutralization and cell protection. In contrast to the sarcoplasmic reticulum + here potassium channels have been clearly ...
متن کاملEnzyme function and membrane lipids.
Biomembranes are built upon a lipid bimolecular ' matrix and intrinsic membrane enzymes can penetrate partially or totally span this bilayer, e.g. the cytochrome oxidase (Frey et al., 1978). Protein-lipid interactions are therefore important for such enzymes, determining their organization and their function (Gennis & Jonas, 1977; Sandermann, 1978; Chapman et al., 1979). In recent years an incr...
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ژورنال
عنوان ژورنال: Nature Reviews Neuroscience
سال: 2014
ISSN: 1471-003X,1471-0048
DOI: 10.1038/nrn3701